Herpes Simplex Virus (HSV-2) infection is one of the most common sexually transmitted diseases in the United States. Following infection or exposure to pathogens, the body responds by producing antibodies, otherwise known as immunoglobulins, to fight the offending agent. Immunoglobulins are specific for each such agent and their presence in the blood allows scientists and doctors to test for them to establish whether a person has ever been exposed to the agent. Although there are others, IgG and IgM are the most relevant immunoglobulins to infections, including HSV (type 1 and 2) infections. Upon initial exposure, the body first responds with IgM immunoglobulins; the IgG immunoglobulin response follows. The IgG antibody remains positive for life, making it helpful in diagnosing patients that are asymptomatic carriers. Over time, the IgM response abates. By looking at IgM and IgG levels, scientists and doctors can determine not only whether a person has ever been exposed to the agent in question, but also whether it was a recent exposure or one in the remote past.
Herpes simplex virus 2 (HSV-2) medical expert witness specialties include STI/STDs, infectious disease, pediatric infectious disease, gynecology, and urology.